nocebo effect

noun

: the development of adverse side effects or worsening in the condition of a patient that occurs in response to medical treatment but cannot be considered due to the specific treatment used
With a nocebo effect, if test subjects believe there may be side effects, they often experience them. Again, expectations shape reality.Sanjay Gupta

Examples of nocebo effect in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Encouraging a more thoughtful and grounded relationship with health information online could be a key step in mitigating the impact of the nocebo effect. Peter Suciu, Forbes.com, 27 Mar. 2025 Marino, who watched the video, told the San Diego Union-Tribune a nocebo effect could explain Faiivae's reaction since his symptoms did not suggest an overdose. Miriam Fauzia, USA TODAY, 25 Aug. 2021 The data clearly indicated that a nocebo effect was occurring – in other words, participants were experiencing an entirely psychological phenomenon in which a harmless substance causes a harmful effect. Elsbeth Sites, Discover Magazine, 3 June 2014

Word History

First Known Use

1969, in the meaning defined above

Time Traveler
The first known use of nocebo effect was in 1969

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Cite this Entry

“Nocebo effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nocebo%20effect. Accessed 5 Jul. 2026.

Medical Definition

nocebo effect

noun
: the development of adverse side effects or worsening in the condition of a patient that occurs in response to medical treatment but cannot be considered due to the specific treatment used
With a nocebo effect, if test subjects believe there may be side effects, they often experience them. Again, expectations shape reality.Sanjay Gupta, Chasing Life: New Discoveries In The Search For Immortality …
The placebo effect has an evil twin: the nocebo effect, in which dummy pills and negative expectations can produce harmful effects.Helen Pilcher, New Scientist
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